The COAPTIUM® CONNECT system from TISSIUM
Peripheral nerve injuries carry a significant burden, often resulting in impaired nerve function, reduced dexterity and a diminished quality of life.
Traditional microsurgical repair with sutures, while effective, presents challenges, such as inconsistent functional recovery and the risk of additional nerve trauma.
The need for disruptive technologies in nerve repair is evident, and Tissium’s COAPTIUM® Connect System offers an atraumatic, sutureless method for the coaptation of severed nerves.
Study overview and key results
A prospective, single-arm study was conducted in patients with digital nerve injuries to evaluate the COAPTIUM® Connect System.
The trial enrolled 12 patients, 10 of whom completed the one-year follow-up period. Results showed 100% procedural success, defined as successful atraumatic sutureless coaptation using the polymer-assisted coaptation device.
All patients regained full flexion and extension of the injured finger, reported no pain (VAS pain score) at 12 months, and no device-related complications were reported throughout the 12-month follow-up period. Additionally, no neuromas were observed.
A major advance in nerve surgery
The COAPTIUM® Connect System was designed for consistent, atraumatic, sutureless nerve repair. It leverages Tissium’s unique biopolymer platform and consists of a light-activated, bioresorbable surgical polymer and a protective coaptation chamber.
“In my 30 years of experience in nerve repair, this is the first product whose clinical results have exceeded my expectations. All patients were pain-free and achieved excellent outcomes” said Professor Randy Bindra, principal trial investigator.
Dr. Michael Wagels, Director of the Australian Centre for Complex Integrated Surgical Solutions, added: “I’m optimistic that this new technology will bring us closer to improved long-term nerve regeneration by eliminating the need for sutures.”
The COAPTIUM® Connect System represents a significant advancement in nerve surgery, offering an innovative and atraumatic method for the coaptation of severed nerves. By eliminating the need for microsutures, this technology simplifies nerve repair while preserving nerve integrity and function.
Recognition and support for French tech
In addition to these clinical advances, Tissium has been selected for the 2024 French Tech 120 program.
This program, supported by the French government, aims to support 120 high-growth French businesses, offering them support in international development, financing and market access.
This recognition underscores Tissium’s potential to become a global leader in medical technology.
In conclusion, the COAPTIUM® CONNECT system represents a significant advance in nerve repair.